Share the diagnostic criteria and examination items of chancroid

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Share the Diagnostic Criteria and Examination Items of Chancroid



Chancroid is a sexually transmitted infection (STI) caused by the bacterium Haemophilus ducreyi. It is characterized by painful, ulcerative lesions on the genitals or surrounding areas.

Diagnostic Criteria:

Clinical Manifestations:

Painful, punched-out ulcers with a raised, beefy red border

Lymphadenopathy (inflammation of lymph nodes) in the groin, often unilateral

Tenderness and discomfort during urination or intercourse

Laboratory Tests:

Bacterial culture of the lesion

Gram stain of the lesion exudate

Serological tests (e.g., enzyme-linked immunosorbent assay [ELISA])

Examination Items:


Detailed sexual history, including number of partners and condom use

Risk factors for STIs (e.g., unprotected sex, multiple partners)

Onset and duration of symptoms

Physical Examination:

Anogenital Examination:

Inspection of the genitals and surrounding areas for ulcers, vesicles, or other lesions

Palpation of lymph nodes for enlargement or tenderness

Lymphadenopathy Evaluation:

Assessment of groin lymph nodes for size, consistency, and tenderness

Fluctuation or fluctuant masses may indicate abscess formation

Systemic Examination:

General inspection for signs of fever or systemic symptoms

Laboratory Examination:

Bacterial Culture:

Swabs are taken from the ulcerated lesion and inoculated onto specific culture media

H. ducreyi colonies, if present, are typically grayish-white and produce a distinctive odor

Gram Stain:

A stained smear of the lesion exudate is examined under a microscope

H. ducreyi bacteria appear as short, Gram-negative rods with bipolar staining (ends are darker)

Serological Tests:

Blood tests may detect antibodies against H. ducreyi

ELISA is commonly used to detect IgG antibodies, which indicate past exposure to the bacteria

Differential Diagnosis:

Herpes simplex virus infection


Lymphogranuloma venereum

Granuloma inguinale

Other STIs


Antibiotic therapy, typically with azithromycin or ceftriaxone

Treatment of any accompanying lymphadenopathy or abscesses

Sexual partner notification and treatment


Consistent and correct condom use during sexual activity

Limiting the number of sexual partners

Regular STI screening for individuals at risk


Untreated chancroid can lead to complications such as:

Lymphadenitis (inflammation of lymph nodes)

Abscess formation


Increased risk of HIV transmission

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