Hepatitis B virus core antibody alone

Hepatitis B Virus Core Antibody Alone

Hepatitis B virus (HBV) is a liver infection that can cause both acute and chronic disease. The hepatitis B virus core antibody (anti-HBc) is a marker of past or present HBV infection. It is one of the three main serological markers of HBV infection, along with the hepatitis B surface antigen (HBsAg) and the hepatitis B e antigen (HBeAg).

Anti-HBc can be detected in the blood within 1-2 weeks after infection with HBV. It usually persists for life, even if the infection has resolved. The presence of anti-HBc alone, without HBsAg or HBeAg, indicates a past HBV infection that has resolved. This is known as resolved HBV infection or inactive HBV infection.

Resolved HBV infection is usually asymptomatic, but it can sometimes cause liver damage. People with resolved HBV infection are at risk of developing chronic HBV infection if they are re-exposed to the virus.

Diagnosis of HBV Infection

Anti-HBc is used to diagnose HBV infection, along with HBsAg and HBeAg. The presence of HBsAg indicates acute or chronic HBV infection. The presence of HBeAg indicates that the infection is active and contagious.

Anti-HBc alone is not diagnostic of acute HBV infection. It can take up to 6 months for anti-HBc to develop after infection, so it may not be present in the early stages of the disease.

Treatment of HBV Infection

There is no cure for HBV infection, but there are treatments that can help to suppress the virus and reduce the risk of liver damage. Treatment is typically recommended for people with chronic HBV infection who have evidence of liver damage or who are at high risk of developing liver damage.

Prevention of HBV Infection

The HBV vaccine is the most effective way to prevent HBV infection. The vaccine is safe and effective, and it is recommended for all infants and children. The vaccine is also recommended for ***s who are at risk of infection, such as healthcare workers, people who travel to areas where HBV is common, and people who have sex with multiple partners.

Outlook for People with Hepatitis B Virus Core Antibody Alone

The outlook for people with anti-HBc alone is generally good. Most people with resolved HBV infection do not experience any symptoms or liver damage. However, people with resolved HBV infection are at risk of developing chronic HBV infection if they are re-exposed to the virus.

It is important for people with anti-HBc alone to be aware of their risk of re-infection and to take steps to avoid exposure to the virus. They should also be vaccinated against HBV if they have not already been vaccinated.

Additional Information

The hepatitis B virus core antibody is a marker of past or present HBV infection.

Anti-HBc alone indicates a past HBV infection that has resolved.

Resolved HBV infection is usually asymptomatic, but it can sometimes cause liver damage.

People with resolved HBV infection are at risk of developing chronic HBV infection if they are re-exposed to the virus.

The HBV vaccine is the most effective way to prevent HBV infection.

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